Processor: Motorola 68000 16/32-bit processor @ 7.67 MHz (MC68HC000, CMOS version)
Co-processor: Zilog Z80 8-bit @ 3.58 MHz
Video display processor Yamaha YM7101, derivative of the VDP from the Sega Master System
Memory: 64K work RAM (68000), 64K video RAM, 8K work RAM (Z80)

Later hardware had an internal 1Kx16 ROM for the license display screen.

Display palette: 512 colors (3:3:3 RGB)
Onscreen colors: 64 (normal) or 183 (shadow/highlight mode)
Maximum onscreen sprites: 80 (320-pixel wide display) or 64 (256-pixel wide display)
Resolution: 256×224, 256×448, 320×224, 320×448, (PAL and NTSC)

256×240, 320×240, 256×480, 320×480 (PAL only), 256×192 (SMS games only)

Sound: Yamaha YM2612 5 channel FM and 1 channel FM/PCM, Texas Instruments SN76489 4 channel PSG (Programmable Sound Generator)